Rédaction Africa Links 24 with Damian Garde
Published on 2024-03-12 13:21:36
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Acadia Pharmaceuticals recently faced a setback when their treatment for schizophrenia, pimavanserin, failed to meet its primary goal in a pivotal study. The drug did not outperform placebo in reducing negative symptoms of schizophrenia, leading to a significant drop in the company’s share price. This unexpected outcome has interrupted Acadia’s plans to expand the use of pimavanserin beyond its current approval for treating hallucinations and delusions in Parkinson’s disease patients.
On a more positive note, Madrigal Pharmaceuticals is on the brink of launching a groundbreaking treatment for fatty liver disease, known as MASH. The drug resmetirom is expected to receive FDA approval soon, offering hope for patients suffering from this condition. MASH results from the accumulation of fat in the liver, leading to inflammation and scarring. Resmetirom targets a specific protein in the liver to reduce fat, inflammation, and scarring, potentially preventing the progression to more severe liver conditions.
In other news, Eli Lilly’s Alzheimer’s drug faced a delay in FDA approval, causing a slight decline in the company’s stock price. The market’s lowered expectations for this drug indicate a shift in focus towards other promising treatments in Lilly’s portfolio. This delay could also impact perceptions of the company’s future Alzheimer’s treatments, highlighting the unpredictable nature of drug development and regulatory processes.
The latest update in the GLP-1 competition involves the FDA approving cardiovascular benefits for Novo Nordisk’s Wegovy. This decision could give Novo a competitive edge over Eli Lilly’s Zepbound in the obesity treatment market. The labeling update emphasizes the cardiovascular advantages of Wegovy, potentially influencing physician prescribing decisions and patient outcomes.
In addition to these developments, there are ongoing discussions about the impact of rigid rules at methadone clinics on patients’ recovery from opioid addiction. President Biden’s budget proposal aims to address spending and tax goals, reflecting his administration’s priorities. New regulations in methadone treatments are set to take effect, raising questions about potential shifts in addiction treatment strategies.
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